Lymphocyte Markers

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Gangliosides as markers for murine lymphocyte subpopulations

Antibodies to GM1 ganglioside were used to study murine lymphocyte populations. In A, AKR, and BALB/c mice, anti-GM1 reacts with thymocytes and peripheral T cells. This reactivity of anti-GM1, studied by immunofluorescence, is independent of Thy-1 type and appears to be related to the reactivity of cross-reacting antibodies to asialo GM1 and GD1b, rather than GM1 itself. In addition, a subpopul...

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Lymphocyte Activation Markers in Pediatric Kidney Transplant Recipients

BACKGROUND AND OBJECTIVES The role of CD4+CD25+ T regulatory cells (Tregs) in immune tolerance in experimental transplantation is very important but the clinical significance of circulating Tregs in the peripheral blood is undetermined. We evaluated the association between the frequency of T cell activation markers CD25 and CD71 and clinical parameters that may affect the level of these T cell ...

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Suppression associated lymphocyte markers in lesions of sarcoidosis.

The presence within the epithelioid granulomas of sarcoidosis of lymphocytes of the "helper" (T4 positive) phenotype suggests that, as in granulomatous diseases of known aetiology, active cell mediated immunity plays a part in the disease. It has, however, been noted that T8 positive lymphocytes are also found on occasion in the granulomas. The presence of cells bearing markers associated with ...

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Prognostic Value of Lymphocyte Surface Markers in Acute Myeloid Leukemia

We studied the expression of cell surface antigens associated with myeloid and lymphoid leukemias on bone marrowderived blast cells from 339 patients with newly diagnosed de novo acute myeloid leukemia (AML) enrolled on Cancer and Leukemia Group B (CALGB) chemotherapy protocols. Surprisingly, of 211 cases studied for the expression of CD2 (T-cell marker, sheep erythrocyte binding receptor for T...

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Expression of cell surface markers after human B lymphocyte activation.

The fate of two recently described human B lymphocyte-specific antigens (B1 and B2) was studied after B-cell activation in vivo and in vitro. Whereas both B1 and B2 were present on virtually all B cells from normal lymph nodes, B2 was absent from approximately 50% of B cells from hyperplastic lymph nodes. When B cells from spleen, tonsil, or peripheral blood were stimulated in vitro with pokewe...

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ژورنال

عنوان ژورنال: Proceedings of the Royal Society of Medicine

سال: 1976

ISSN: 0035-9157

DOI: 10.1177/003591577606900907